DNA Ligase IV Prevents Replication Fork Stalling and Promotes Cellular Proliferation in Triple Negative Breast Cancer

DNA damage is a hallmark of cancer, and mutation and misregulation of proteins that maintain genomic fidelity are associated with the development of multiple cancers. DNA double strand breaks are arguably considered the most deleterious type of DNA damage. The nonhomologous end-joining (NHEJ) pathwa...

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Detalles Bibliográficos
Autores principales: Joshi, Rashmi R., Ali, Sk Imran, Ashley, Amanda K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6374816/
https://www.ncbi.nlm.nih.gov/pubmed/30838131
http://dx.doi.org/10.1155/2019/9170341

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6374816/
https://www.ncbi.nlm.nih.gov/pubmed/30838131
http://dx.doi.org/10.1155/2019/9170341

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