Time dependent degeneration of the nigrostriatal tract in mice with 6-OHDA lesioned medial forebrain bundle and the effect of activin A on l-Dopa induced dyskinesia

BACKGROUND: Accurately assessing promising therapeutic interventions for human diseases depends, in part, on the reproducibility of preclinical disease models. With the development of transgenic mice, the rapid adaptation of a 6-OHDA mouse model of Parkinson’s disease that was originally described f...

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Detalles Bibliográficos
Autores principales: Rentsch, Peggy, Stayte, Sandy, Morris, Gary P., Vissel, Bryce
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6374903/
https://www.ncbi.nlm.nih.gov/pubmed/30760214
http://dx.doi.org/10.1186/s12868-019-0487-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6374903/
https://www.ncbi.nlm.nih.gov/pubmed/30760214
http://dx.doi.org/10.1186/s12868-019-0487-7

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