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LRG-1 promotes pancreatic cancer growth and metastasis via modulation of the EGFR/p38 signaling

BACKGROUND: The abnormal expression of leucine-rich-alpha-2-glycoprotein 1 (LRG-1) is reported to be associated with multiple malignancies, but its role in the progression of pancreatic ductal adenocarcinoma (PDAC) remains to be determined. METHODS: The expression of LRG-1 was assessed in PDAC tissu...

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Detalles Bibliográficos
Autores principales: Xie, Zhi-Bo, Zhang, Yi-Fan, Jin, Chen, Mao, Yi-Shen, Fu, De-Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6374912/
https://www.ncbi.nlm.nih.gov/pubmed/30760292
http://dx.doi.org/10.1186/s13046-019-1088-0