Cargando…
LRG-1 promotes pancreatic cancer growth and metastasis via modulation of the EGFR/p38 signaling
BACKGROUND: The abnormal expression of leucine-rich-alpha-2-glycoprotein 1 (LRG-1) is reported to be associated with multiple malignancies, but its role in the progression of pancreatic ductal adenocarcinoma (PDAC) remains to be determined. METHODS: The expression of LRG-1 was assessed in PDAC tissu...
Autores principales: | Xie, Zhi-Bo, Zhang, Yi-Fan, Jin, Chen, Mao, Yi-Shen, Fu, De-Liang |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6374912/ https://www.ncbi.nlm.nih.gov/pubmed/30760292 http://dx.doi.org/10.1186/s13046-019-1088-0 |
Ejemplares similares
-
LRG1 promotes angiogenesis by modulating endothelial TGFß signalling
por: Wang, Xiaomeng, et al.
Publicado: (2013) -
LRG1 Promotes Metastatic Dissemination of Melanoma through Regulating EGFR/STAT3 Signalling
por: Kwan, Yuet Ping, et al.
Publicado: (2021) -
Crystal structure of LRG1 and the functional significance of LRG1 glycan for LPHN2 activation
por: Yang, Jimin, et al.
Publicado: (2023) -
LRG1 is an adipokine that promotes insulin sensitivity and suppresses inflammation
por: Choi, Chan Hee J, et al.
Publicado: (2022) -
LRG-1 enhances the migration of thyroid carcinoma cells through promotion of the epithelial-mesenchymal transition by activating MAPK/p38 signaling
por: Ban, Zhengfeng, et al.
Publicado: (2019)