Permeation-enhancing effects and mechanisms of O-acylterpineol on isosorbide dinitrate: mechanistic insights based on ATR-FTIR spectroscopy, molecular modeling, and CLSM images

The present study aimed to evaluate the penetration activity of O-acylterpineol derivatives both in vitro and in vivo, and to investigate the enhancing mechanism of O-acylterpineol derivatives which were synthesized by α-terpineol and fatty acid. The promoting activities on the isosorbide dinitrate...

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Detalles Bibliográficos
Autores principales: Li, Yan, Wang, Chunyan, Wang, Jian, Chu, Tianzhe, Zhao, Linlin, Zhao, Ligang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6374923/
https://www.ncbi.nlm.nih.gov/pubmed/30744434
http://dx.doi.org/10.1080/10717544.2018.1561764

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6374923/
https://www.ncbi.nlm.nih.gov/pubmed/30744434
http://dx.doi.org/10.1080/10717544.2018.1561764

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