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(5R)-5-hydroxytriptolide inhibits the inflammatory cascade reaction in astrocytes

Many studies have shown that (5R)-5-hydroxytriptolide is the optimal modified analogue of triptolide, possessing comparable immunosuppressive activity but much lower cytotoxicity than triptolide. Whether (5R)-5-hydroxytriptolide has preventive effects on neuroinflammation is unclear. This study was...

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Detalles Bibliográficos
Autores principales: Cui, Yan-Qiu, Zheng, Yan, Tan, Gui-Lian, Zhang, Dong-Mei, Wang, Jun-Ya, Wang, Xiao-Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6375032/
https://www.ncbi.nlm.nih.gov/pubmed/30688278
http://dx.doi.org/10.4103/1673-5374.249240