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Electrophilic nitro-oleic acid reverses obesity-induced hepatic steatosis

Non-alcoholic fatty liver disease (NAFLD) is linked to obesity and insulin resistance and is the most prevalent chronic liver disease. During the development of obesity and NAFLD, mitochondria adapt to the increased lipid load in hepatocytes by increasing the rate of fatty acid oxidation. In concert...

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Detalles Bibliográficos
Autores principales: Khoo, Nicholas K.H., Fazzari, Marco, Chartoumpekis, Dionysios V., Li, Lihua, Guimaraes, Danielle Aparecida, Arteel, Gavin E., Shiva, Sruti, Freeman, Bruce A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6375063/
https://www.ncbi.nlm.nih.gov/pubmed/30769284
http://dx.doi.org/10.1016/j.redox.2019.101132