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Antenatal melatonin modulates an enhanced antioxidant/pro-oxidant ratio in pulmonary hypertensive newborn sheep

Chronic hypobaric hypoxia during fetal and neonatal life induces neonatal pulmonary hypertension. Hypoxia and oxidative stress are driving this condition, which implies an increase generation of reactive oxygen species (ROS) and/or decreased antioxidant capacity. Melatonin has antioxidant properties...

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Detalles Bibliográficos
Autores principales: Gonzalez-Candia, Alejandro, Veliz, Marcelino, Carrasco-Pozo, Catalina, Castillo, Rodrigo L., Cárdenas, J. Cesar, Ebensperger, Germán, Reyes, Roberto V., Llanos, Aníbal J., Herrera, Emilio A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6375064/
https://www.ncbi.nlm.nih.gov/pubmed/30771751
http://dx.doi.org/10.1016/j.redox.2019.101128