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Partial sciatic nerve ligation leads to an upregulation of Ni(2+)-resistant T-type Ca(2+) currents in capsaicin-responsive nociceptive dorsal root ganglion neurons
BACKGROUND: Neuropathic pain resulting from peripheral nerve lesions is a common medical condition, but current analgesics are often insufficient. The identification of key molecules involved in pathological pain processing is a prerequisite for the development of new analgesic drugs. Hyperexcitabil...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6375107/ https://www.ncbi.nlm.nih.gov/pubmed/30804682 http://dx.doi.org/10.2147/JPR.S138708 |