Partial sciatic nerve ligation leads to an upregulation of Ni(2+)-resistant T-type Ca(2+) currents in capsaicin-responsive nociceptive dorsal root ganglion neurons

BACKGROUND: Neuropathic pain resulting from peripheral nerve lesions is a common medical condition, but current analgesics are often insufficient. The identification of key molecules involved in pathological pain processing is a prerequisite for the development of new analgesic drugs. Hyperexcitabil...

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Detalles Bibliográficos
Autores principales: Jeub, Monika, Taha, Omneya, Opitz, Thoralf, Racz, Ildiko, Pitsch, Julika, Becker, Albert, Beck, Heinz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6375107/
https://www.ncbi.nlm.nih.gov/pubmed/30804682
http://dx.doi.org/10.2147/JPR.S138708

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