A cautionary note on the selectivity of oncolytic poxviruses

BACKGROUND: Oncolytic viruses selectively infect cancer cells while avoiding infection of normal cells. Usually, selectivity is demonstrated by injecting a virus into tumor-bearing mice and observing infection and lysis of tumor cells without infection of other tissues. The general view is that this...

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Detalles Bibliográficos
Autores principales: Tang, Bingtao, Guo, Zong Sheng, Bartlett, David L, Liu, Jia, McFadden, Grant, Shisler, Joanna L, Roy, Edward J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6375109/
https://www.ncbi.nlm.nih.gov/pubmed/30805315
http://dx.doi.org/10.2147/OV.S189832

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6375109/
https://www.ncbi.nlm.nih.gov/pubmed/30805315
http://dx.doi.org/10.2147/OV.S189832

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