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Inhibition of PTGS1 promotes osteogenic differentiation of adipose-derived stem cells by suppressing NF-kB signaling

BACKGROUND: Tissue inflammation is an important problem in the field of human adipose-derived stem cell (ASC)-based therapeutic bone regeneration. Many studies indicate that inflammatory cytokines are disadvantageous for osteogenic differentiation and bone formation. Therefore, overcoming inflammati...

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Detalles Bibliográficos
Autores principales: Wang, Yuejun, Liu, Yunsong, Zhang, Min, Lv, Longwei, Zhang, Xiao, Zhang, Ping, Zhou, Yongsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6375160/
https://www.ncbi.nlm.nih.gov/pubmed/30760327
http://dx.doi.org/10.1186/s13287-019-1167-3