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Modelling cardiac fibrosis using three-dimensional cardiac microtissues derived from human embryonic stem cells

BACKGROUND: Cardiac fibrosis is the most common pathway of many cardiac diseases. To date, there has been no suitable in vitro cardiac fibrosis model that could sufficiently mimic the complex environment of the human heart. Here, a three-dimensional (3D) cardiac sphere platform of contractile cardia...

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Detalles Bibliográficos
Autores principales: Lee, Mi-Ok, Jung, Kwang Bo, Jo, Seong-Jae, Hyun, Sung-Ae, Moon, Kyoung-Sik, Seo, Joung-Wook, Kim, Sang-Heon, Son, Mi-Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6375184/
https://www.ncbi.nlm.nih.gov/pubmed/30809271
http://dx.doi.org/10.1186/s13036-019-0139-6