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Neutrophilic proteolysis in the cystic fibrosis lung correlates with a pathogenic microbiome

BACKGROUND: Studies of the cystic fibrosis (CF) lung microbiome have consistently shown that lung function decline is associated with decreased microbial diversity due to the dominance of opportunistic pathogens. However, how this phenomenon is reflected in the metabolites and chemical environment o...

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Detalles Bibliográficos
Autores principales: Quinn, Robert A., Adem, Sandeep, Mills, Robert H., Comstock, William, DeRight Goldasich, Lindsay, Humphrey, Gregory, Aksenov, Alexander A., Melnik, Alexei V., da Silva, Ricardo, Ackermann, Gail, Bandeira, Nuno, Gonzalez, David J., Conrad, Doug, O’Donoghue, Anthony J., Knight, Rob, Dorrestein, Pieter C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6375204/
https://www.ncbi.nlm.nih.gov/pubmed/30760325
http://dx.doi.org/10.1186/s40168-019-0636-3