Activation of Nrf2/Keap1 pathway by oral Dimethylfumarate administration alleviates oxidative stress and age-associated infertility might be delayed in the mouse ovary

BACKGROUND: Age-associated infertility is a problem worldwide, and management of oxidative stress is known to be essential. Nuclear factor-E2-related factor 2 (Nrf2)/Kelch-like ECH-associated protein 1 (Keap1)-antioxidant response element (ARE) signaling pathway works as an essential defense mechani...

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Detalles Bibliográficos
Autores principales: Akino, Nana, Wada-Hiraike, Osamu, Isono, Wataru, Terao, Hiromi, Honjo, Harunori, Miyamoto, Yuichiro, Tanikawa, Michihiro, Sone, Kenbun, Hirano, Mana, Harada, Miyuki, Hirata, Tetsuya, Hirota, Yasushi, Koga, Kaori, Oda, Katsutoshi, Fujii, Tomoyuki, Osuga, Yutaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6375213/
https://www.ncbi.nlm.nih.gov/pubmed/30760288
http://dx.doi.org/10.1186/s12958-019-0466-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6375213/
https://www.ncbi.nlm.nih.gov/pubmed/30760288
http://dx.doi.org/10.1186/s12958-019-0466-y

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