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Analysis of core protein clusters identifies candidate variable sites conferring metronidazole resistance in Helicobacter pylori

BACKGROUND: Metronidazole is one of the first-line drugs of choice in the standard triple therapy used to eradicate Helicobacter pylori infection. Hence, the global emergence of metronidazole resistance in Hp poses a major challenge to health professionals. Inactivation of RdxA is known to be a majo...

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Detalles Bibliográficos
Autores principales: Chua, Eng-Guan, Debowski, Aleksandra W, Webberley, K Mary, Peters, Fanny, Lamichhane, Binit, Loke, Mun-Fai, Vadivelu, Jamuna, Tay, Chin-Yen, Marshall, Barry J, Wise, Michael J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6375344/
https://www.ncbi.nlm.nih.gov/pubmed/30792865
http://dx.doi.org/10.1093/gastro/goy048