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Analysis of core protein clusters identifies candidate variable sites conferring metronidazole resistance in Helicobacter pylori
BACKGROUND: Metronidazole is one of the first-line drugs of choice in the standard triple therapy used to eradicate Helicobacter pylori infection. Hence, the global emergence of metronidazole resistance in Hp poses a major challenge to health professionals. Inactivation of RdxA is known to be a majo...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6375344/ https://www.ncbi.nlm.nih.gov/pubmed/30792865 http://dx.doi.org/10.1093/gastro/goy048 |