Comparative analysis of mutational robustness of the intrinsically disordered viral protein VPg and of its interactor eIF4E

Conformational intrinsic disorder is a feature present in many virus proteins. Intrinsically disordered regions (IDRs) have weaker structural requirement than ordered regions and mutations in IDRs could have a lower impact on the virus fitness. This could favor its exploration of adaptive solutions....

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Detalles Bibliográficos
Autores principales: Walter, Jocelyne, Charon, Justine, Hu, Yihua, Lachat, Joy, Leger, Thomas, Lafforgue, Guillaume, Barra, Amandine, Michon, Thierry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6375565/
https://www.ncbi.nlm.nih.gov/pubmed/30763345
http://dx.doi.org/10.1371/journal.pone.0211725

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6375565/
https://www.ncbi.nlm.nih.gov/pubmed/30763345
http://dx.doi.org/10.1371/journal.pone.0211725

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