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Monotherapy with a low-dose lipopeptide HIV fusion inhibitor maintains long-term viral suppression in rhesus macaques

Combination antiretroviral therapy (cART) dramatically improves survival of HIV-infected patients, but lifelong treatment can ultimately result in cumulative toxicities and drug resistance, thus necessitating the development of new drugs with significantly improved pharmaceutical profiles. We recent...

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Detalles Bibliográficos
Autores principales: Chong, Huihui, Xue, Jing, Zhu, Yuanmei, Cong, Zhe, Chen, Ting, Wei, Qiang, Qin, Chuan, He, Yuxian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6375636/
https://www.ncbi.nlm.nih.gov/pubmed/30716118
http://dx.doi.org/10.1371/journal.ppat.1007552