Lens differentiation is controlled by the balance between PDGF and FGF signaling

How multiple receptor tyrosine kinases coordinate cell fate determination is yet to be elucidated. We show here that the receptor for platelet-derived growth factor (PDGF) signaling recruits the p85 subunit of Phosphoinositide 3-kinase (PI3K) to regulate mammalian lens development. Activation of PI3...

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Detalles Bibliográficos
Autores principales: Li, Hongge, Mao, Yingyu, Bouaziz, Michael, Yu, Honglian, Qu, Xiuxia, Wang, Fen, Feng, Gen-Sheng, Shawber, Carrie, Zhang, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6375662/
https://www.ncbi.nlm.nih.gov/pubmed/30716082
http://dx.doi.org/10.1371/journal.pbio.3000133

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6375662/
https://www.ncbi.nlm.nih.gov/pubmed/30716082
http://dx.doi.org/10.1371/journal.pbio.3000133

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