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Group 2 innate lymphoid cells (ILC2) are regulated by stem cell factor during chronic asthmatic disease

Stem cell factor (SCF) binds to the receptor c-Kit that is expressed on a number of myeloid and lymphoid cell populations, including Type 2 innate lymphoid cells (ILC2). However the importance of the SCF/c-Kit interaction in ILC2 has not been studied. Here we investigate the role of a specific SCF i...

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Detalles Bibliográficos
Autores principales: Fonseca, Wendy, Rasky, Andrew J, Ptaschinski, Catherine, Morris, Susan H, Best, Shannon K.K., Phillips, Martin, Malinczak, Carrie-Anne, Lukacs, Nicholas W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6375742/
https://www.ncbi.nlm.nih.gov/pubmed/30617299
http://dx.doi.org/10.1038/s41385-018-0117-1