Treatment Strategies in Diffuse Midline Gliomas With the H3K27M Mutation: The Role of Convection-Enhanced Delivery in Overcoming Anatomic Challenges

Diffuse midline gliomas harboring the H3 K27M mutation—including the previously named diffuse intrinsic pontine glioma (DIPG)—are lethal high-grade pediatric brain tumors that are inoperable and without cure. Despite numerous clinical trials, the prognosis remains poor, with a median survival of ~1...

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Detalles Bibliográficos
Autores principales: Himes, Benjamin T., Zhang, Liang, Daniels, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6375835/
https://www.ncbi.nlm.nih.gov/pubmed/30800634
http://dx.doi.org/10.3389/fonc.2019.00031

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6375835/
https://www.ncbi.nlm.nih.gov/pubmed/30800634
http://dx.doi.org/10.3389/fonc.2019.00031

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