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Mechanisms contributing to persistently activated cell phenotypes in pulmonary hypertension

Chronic pulmonary hypertension (PH) is characterized by the accumulation of persistently activated cell types in the pulmonary vessel exhibiting aberrant expression of genes involved in apoptosis resistance, proliferation, inflammation and extracellular matrix (ECM) remodelling. Current therapies fo...

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Detalles Bibliográficos
Autores principales: Hu, Cheng‐Jun, Zhang, Hui, Laux, Aya, Pullamsetti, Soni S., Stenmark, Kurt R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6375873/
https://www.ncbi.nlm.nih.gov/pubmed/29920674
http://dx.doi.org/10.1113/JP275857