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Modulation of Intestinal Epithelial Permeability by Plasma from Patients with Crohn’s Disease in a Three-dimensional Cell Culture Model

Intestinal epithelial barrier is affected by multiple factors, such as tumour necrosis factor-α (TNF-α). Plasma concentration of TNF-α is higher in patients with Crohn’s disease (CD) than healthy controls (HC) and correlates positively with disease activity. This study aimed to determine the effect...

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Detalles Bibliográficos
Autores principales: Xu, Pan, Elamin, Elhaseen, Elizalde, Montserrat, Bours, Paul P. H. A., Pierik, Marieke J., Masclee, Ad A. M., Jonkers, Daisy M. A. E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6375954/
https://www.ncbi.nlm.nih.gov/pubmed/30765731
http://dx.doi.org/10.1038/s41598-018-38322-8