Oncogenic Y68 frame shift mutation of PTEN represents a mechanism of docetaxel resistance in endometrial cancer cell lines

In this study, we aimed to identify mutations of key genes associated with docetaxel resistance in nine endometrial cancer cell lines. Endometrial cancers are associated with several critical gene mutations, including PIK3A, PTEN, and KRAS. Different gene mutations in endometrial cancer cells have v...

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Detalles Bibliográficos
Autores principales: Zhang, Haiyang, Wang, Song, Cacalano, Nicholas, Zhu, He, Liu, Qiuju, Xie, Michael, Kamrava, Mitchell, Konecny, Gottfried, Jin, Shunzi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6375989/
https://www.ncbi.nlm.nih.gov/pubmed/30765787
http://dx.doi.org/10.1038/s41598-019-38585-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6375989/
https://www.ncbi.nlm.nih.gov/pubmed/30765787
http://dx.doi.org/10.1038/s41598-019-38585-9

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