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Oncogenic Y68 frame shift mutation of PTEN represents a mechanism of docetaxel resistance in endometrial cancer cell lines
In this study, we aimed to identify mutations of key genes associated with docetaxel resistance in nine endometrial cancer cell lines. Endometrial cancers are associated with several critical gene mutations, including PIK3A, PTEN, and KRAS. Different gene mutations in endometrial cancer cells have v...
Autores principales: | Zhang, Haiyang, Wang, Song, Cacalano, Nicholas, Zhu, He, Liu, Qiuju, Xie, Michael, Kamrava, Mitchell, Konecny, Gottfried, Jin, Shunzi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6375989/ https://www.ncbi.nlm.nih.gov/pubmed/30765787 http://dx.doi.org/10.1038/s41598-019-38585-9 |
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