Nematicidal and insecticidal activities of halogenated indoles

Parasite death via ion channel activations is the hallmark of anthelmintic and antiparasitic drugs. Glutamate gated chloride channel (GluCl) is a prominent targets for drug selection and design in parasitology. We report several iodine-fluorine based lead activators of GluCl by computational studies...

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Detalles Bibliográficos
Autores principales: Rajasekharan, Satish Kumar, Lee, Jin-Hyung, Ravichandran, Vinothkannan, Kim, Jin-Cheol, Park, Jae Gyu, Lee, Jintae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6375993/
https://www.ncbi.nlm.nih.gov/pubmed/30765810
http://dx.doi.org/10.1038/s41598-019-38561-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6375993/
https://www.ncbi.nlm.nih.gov/pubmed/30765810
http://dx.doi.org/10.1038/s41598-019-38561-3

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