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Nematicidal and insecticidal activities of halogenated indoles
Parasite death via ion channel activations is the hallmark of anthelmintic and antiparasitic drugs. Glutamate gated chloride channel (GluCl) is a prominent targets for drug selection and design in parasitology. We report several iodine-fluorine based lead activators of GluCl by computational studies...
Autores principales: | Rajasekharan, Satish Kumar, Lee, Jin-Hyung, Ravichandran, Vinothkannan, Kim, Jin-Cheol, Park, Jae Gyu, Lee, Jintae |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6375993/ https://www.ncbi.nlm.nih.gov/pubmed/30765810 http://dx.doi.org/10.1038/s41598-019-38561-3 |
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