Analysis of whole genome-transcriptomic organization in brain to identify genes associated with alcoholism

Alcohol exposure triggers changes in gene expression and biological pathways in human brain. We explored alterations in gene expression in the Pre-Frontal Cortex (PFC) of 65 alcoholics and 73 controls of European descent, and identified 129 genes that showed altered expression (FDR < 0.05) in sub...

Descripción completa

Detalles Bibliográficos
Autores principales: Kapoor, Manav, Wang, Jen-Chyong, Farris, Sean P., Liu, Yunlong, McClintick, Jeanette, Gupta, Ishaan, Meyers, Jacquelyn L., Bertelsen, Sarah, Chao, Michael, Nurnberger, John, Tischfield, Jay, Harari, Oscar, Zeran, Li, Hesselbrock, Victor, Bauer, Lance, Raj, Towfique, Porjesz, Bernice, Agrawal, Arpana, Foroud, Tatiana, Edenberg, Howard J., Mayfield, R. Dayne, Goate, Alison
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6376002/
https://www.ncbi.nlm.nih.gov/pubmed/30765688
http://dx.doi.org/10.1038/s41398-019-0384-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6376002/
https://www.ncbi.nlm.nih.gov/pubmed/30765688
http://dx.doi.org/10.1038/s41398-019-0384-y

Ejemplares similares