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CaMello-XR enables visualization and optogenetic control of G(q/11) signals and receptor trafficking in GPCR-specific domains
The signal specificity of G protein-coupled receptors (GPCRs) including serotonin receptors (5-HT-R) depends on the trafficking and localization of the GPCR within its subcellular signaling domain. Visualizing traffic-dependent GPCR signals in neurons is difficult, but important to understand the co...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6376006/ https://www.ncbi.nlm.nih.gov/pubmed/30793039 http://dx.doi.org/10.1038/s42003-019-0292-y |