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CaMello-XR enables visualization and optogenetic control of G(q/11) signals and receptor trafficking in GPCR-specific domains

The signal specificity of G protein-coupled receptors (GPCRs) including serotonin receptors (5-HT-R) depends on the trafficking and localization of the GPCR within its subcellular signaling domain. Visualizing traffic-dependent GPCR signals in neurons is difficult, but important to understand the co...

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Detalles Bibliográficos
Autores principales: Eickelbeck, Dennis, Karapinar, Raziye, Jack, Alexander, Suess, Sandra T., Barzan, Ruxandra, Azimi, Zohre, Surdin, Tatjana, Grömmke, Michelle, Mark, Melanie D., Gerwert, Klaus, Jancke, Dirk, Wahle, Petra, Spoida, Katharina, Herlitze, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6376006/
https://www.ncbi.nlm.nih.gov/pubmed/30793039
http://dx.doi.org/10.1038/s42003-019-0292-y