Metformin inhibits lithocholic acid-induced interleukin 8 upregulation in colorectal cancer cells by suppressing ROS production and NF-kB activity

Metformin, an inexpensive, well-tolerated oral agent that is a commonly used first-line treatment for type 2 diabetes, has become the focus of intense research as a potential anticancer agent. In this study, we describe the inhibitory effect of metformin in interleukin 8 (IL-8) upregulation by litho...

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Detalles Bibliográficos
Autores principales: Nguyen, Thi Thinh, Ung, Trong Thuan, Li, Shinan, Lian, Sen, Xia, Yong, Park, Sun Young, Do Jung, Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6376015/
https://www.ncbi.nlm.nih.gov/pubmed/30765814
http://dx.doi.org/10.1038/s41598-019-38778-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6376015/
https://www.ncbi.nlm.nih.gov/pubmed/30765814
http://dx.doi.org/10.1038/s41598-019-38778-2

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