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Quantifying dynamic mechanisms of auto-regulation in Escherichia coli with synthetic promoter in response to varying external phosphate levels

Escherichia coli have developed one of the most efficient regulatory response mechanisms to phosphate starvation. The machinery involves a cascade with a two-component system (TCS) that relays the external signal to the genetic circuit, resulting in a feedback response. Achieving a quantitative unde...

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Detalles Bibliográficos
Autores principales: Uluşeker, Cansu, Torres-Bacete, Jesús, García, José L., Hanczyc, Martin M., Nogales, Juan, Kahramanoğulları, Ozan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6376016/
https://www.ncbi.nlm.nih.gov/pubmed/30765722
http://dx.doi.org/10.1038/s41598-018-38223-w