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Ex vivo organotypic culture system of precision-cut slices of human pancreatic ductal adenocarcinoma

Pancreatic ductal adenocarcinoma (PDAC) has a poor prognosis, which is mainly due to late diagnosis and profound resistance to treatment. The latter is to a large extent attributed to the tumor stroma that is exceedingly prominent in PDAC and engages in complex interactions with the cancer cells. He...

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Detalles Bibliográficos
Autores principales: Misra, Sougat, Moro, Carlos F., Del Chiaro, Marco, Pouso, Soledad, Sebestyén, Anna, Löhr, Matthias, Björnstedt, Mikael, Verbeke, Caroline S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6376017/
https://www.ncbi.nlm.nih.gov/pubmed/30765891
http://dx.doi.org/10.1038/s41598-019-38603-w