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Ex vivo organotypic culture system of precision-cut slices of human pancreatic ductal adenocarcinoma
Pancreatic ductal adenocarcinoma (PDAC) has a poor prognosis, which is mainly due to late diagnosis and profound resistance to treatment. The latter is to a large extent attributed to the tumor stroma that is exceedingly prominent in PDAC and engages in complex interactions with the cancer cells. He...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6376017/ https://www.ncbi.nlm.nih.gov/pubmed/30765891 http://dx.doi.org/10.1038/s41598-019-38603-w |