Synthesis of Oxazinanones: Intramolecular Cyclization of Amino Acid-Derived Diazoketones via Silica-Supported HClO(4) Catalysis

A Brønsted acid catalyzed intramolecular cyclization of N-Cbz-protected diazoketones, derived from α-amino acids, is described. The reaction proceeds under metal-free conditions and is promoted by ecofriendly silica-supported HClO(4) as the catalyst and methanol as the solvent. This transformation e...

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Detalles Bibliográficos
Autores principales: Gallo, Rafael D. C., Campovilla Jr., Orlando C., Ahmad, Anees, Burtoloso, Antonio C. B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6376066/
https://www.ncbi.nlm.nih.gov/pubmed/30800653
http://dx.doi.org/10.3389/fchem.2019.00062

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6376066/
https://www.ncbi.nlm.nih.gov/pubmed/30800653
http://dx.doi.org/10.3389/fchem.2019.00062

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