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Effect of the live oral attenuated typhoid vaccine, Ty21a, on systemic and terminal ileum mucosal CD4(+) T memory responses in humans

Our current understanding of CD4(+) T-cell-mediated immunity (CMI) elicited by the oral live attenuated typhoid vaccine Ty21a is primarily derived from studies using peripheral blood. Very limited data are available in humans regarding mucosal immunity (especially CD4(+) T) at the site of infection...

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Detalles Bibliográficos
Autores principales: Booth, Jayaum S, Goldberg, Eric, Patil, Seema A, Barnes, Robin S, Greenwald, Bruce D, Sztein, Marcelo B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6376105/
https://www.ncbi.nlm.nih.gov/pubmed/30346608
http://dx.doi.org/10.1093/intimm/dxy070