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Leveraging the Medicines for Malaria Venture malaria and pathogen boxes to discover chemical inhibitors of East Coast fever

Chemotherapy of East Coast fever, a lymphoproliferative cancer-like disease of cattle causing significant economic losses in Africa, is largely dependent on the use of buparvaquone, a drug that was developed in the late 1980's. The disease is caused by the tick-borne protozoan pathogen Theileri...

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Detalles Bibliográficos
Autores principales: Nyagwange, James, Awino, Elias, Tijhaar, Edwin, Svitek, Nicholas, Pelle, Roger, Nene, Vishvanath
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6376154/
https://www.ncbi.nlm.nih.gov/pubmed/30771616
http://dx.doi.org/10.1016/j.ijpddr.2019.01.002