Cargando…
Novel column generation-based optimization approach for poly-pathway kinetic model applied to CHO cell culture
Mathematical modelling can provide precious tools for bioprocess simulation, prediction, control and optimization of mammalian cell-based cultures. In this paper we present a novel method to generate kinetic models of such cultures, rendering complex metabolic networks in a poly-pathway kinetic mode...
Autores principales: | Hagrot, Erika, Oddsdóttir, Hildur Æsa, Mäkinen, Meeri, Forsgren, Anders, Chotteau, Véronique |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6376161/ https://www.ncbi.nlm.nih.gov/pubmed/30809468 http://dx.doi.org/10.1016/j.mec.2018.e00083 |
Ejemplares similares
-
Multiplexed Microfluidic Cartridge for At-Line Protein
Monitoring in Mammalian Cell Culture Processes for Biopharmaceutical
Production
por: Pinto, Inês F., et al.
Publicado: (2021) -
Pilot‐scale process for magnetic bead purification of antibodies directly from non‐clarified CHO cell culture
por: Brechmann, Nils A., et al.
Publicado: (2019) -
Dynamical analysis of antibody aggregation in the CHO cell culture with Thermo Responsive Protein A (TRPA) column
por: Noda, Masahiro, et al.
Publicado: (2013) -
Very High Density of CHO Cells in Perfusion by ATF or TFF in WAVE Bioreactor™. Part I. Effect of the Cell Density on the Process
por: Clincke, Marie-Françoise, et al.
Publicado: (2013) -
Study of a recombinant CHO cell line producing a monoclonal antibody by ATF or TFF external filter perfusion in a WAVE Bioreactor™
por: Clincke, Marie-Françoise, et al.
Publicado: (2011)