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Oncostatin M exerts a protective effect against excessive scarring by counteracting the inductive effect of TGFβ1 on fibrosis markers

Wound healing is a complex physiological process that repairs a skin lesion and produces fibrous tissue. In some cases, this process can lead to hypertrophic scars (HS) or keloid scars (KS), for which the pathophysiology remains poorly understood. Previous studies have reported the presence of oncos...

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Detalles Bibliográficos
Autores principales: Huguier, Vincent, Giot, Jean-Philippe, Simonneau, Marie, Levillain, Pierre, Charreau, Sandrine, Garcia, Martine, Jégou, Jean-François, Bodet, Charles, Morel, Franck, Lecron, Jean-Claude, Favot, Laure
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6376164/
https://www.ncbi.nlm.nih.gov/pubmed/30765798
http://dx.doi.org/10.1038/s41598-019-38572-0