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Matrine Mediates Inflammatory Response via Gut Microbiota in TNBS-Induced Murine Colitis

This study mainly investigated the effect of matrine on TNBS-induced intestinal inflammation in mice. TNBS treatment caused colonic injury and gut inflammation. Matrine (1, 5, and 10 mg/kg) treatment alleviated colonic injury and gut inflammation via reducing bleeding and diarrhea and downregulating...

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Detalles Bibliográficos
Autores principales: Li, Peiyuan, Lei, Jiajun, Hu, Guangsheng, Chen, Xuanmin, Liu, Zhifeng, Yang, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6376167/
https://www.ncbi.nlm.nih.gov/pubmed/30800071
http://dx.doi.org/10.3389/fphys.2019.00028