Chemotherapy priming of the Pancreatic Tumor Microenvironment Promotes Delivery and Anti-Metastasis Efficacy of Intravenous Low-Molecular-Weight Heparin-Coated Lipid-siRNA Complex

Pancreatic ductal adenocarcinoma (PDAC) is a type of malignant tumor with high lethality. Its high tumor cell-density and large variety of extracellular matrix (ECM) components present major barriers for drug delivery. Methods: Paclitaxel-loaded PEGylated liposomes (PTX-Lip) were used as a tumor-pri...

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Detalles Bibliográficos
Autores principales: Yu, Qianwen, Qiu, Yue, Chen, Xiaoxiao, Wang, Xuhui, Mei, Ling, Wu, Haiyao, Liu, Kai, Liu, Yayuan, Li, Man, Zhang, Zhirong, He, Qin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6376180/
https://www.ncbi.nlm.nih.gov/pubmed/30809279
http://dx.doi.org/10.7150/thno.29137

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6376180/
https://www.ncbi.nlm.nih.gov/pubmed/30809279
http://dx.doi.org/10.7150/thno.29137

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