RNA-seq analysis of PHD and VHL inhibitors reveals differences and similarities to the hypoxia response.

Background: Hypoxia-inducible factor (HIF) transcription factors are well known to control the transcriptional response to hypoxia. Given the importance of cellular response to hypoxia, a number of pharmacological agents to interfere with this pathway have been developed and entered pre-clinical or...

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Detalles Bibliográficos
Autores principales: Frost, Julianty, Ciulli, Alessio, Rocha, Sonia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6376255/
https://www.ncbi.nlm.nih.gov/pubmed/30801039
http://dx.doi.org/10.12688/wellcomeopenres.15044.1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6376255/
https://www.ncbi.nlm.nih.gov/pubmed/30801039
http://dx.doi.org/10.12688/wellcomeopenres.15044.1

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