A sequence conserved between CD5 and CD6 binds an FERM domain and exerts a restraint on T‐cell activation

CD5 and CD6 are related surface receptors that limit and promote T‐cell responses. Co‐stimulatory effects of CD6 depend on binding a cell surface ligand, CD166, and recruitment of the intracellular adaptor proteins GADS and SLP‐76 by C‐terminal phosphotyrosines. We have continued to identify interac...

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Detalles Bibliográficos
Autores principales: Breuning, Johannes, Brown, Marion H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6376265/
https://www.ncbi.nlm.nih.gov/pubmed/30460991
http://dx.doi.org/10.1111/imm.13025

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6376265/
https://www.ncbi.nlm.nih.gov/pubmed/30460991
http://dx.doi.org/10.1111/imm.13025

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