Challenges Facing Airway Epithelial Cell-Based Therapy for Cystic Fibrosis

Mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene cause the life-limiting hereditary disease, cystic fibrosis (CF). Decreased or absent functional CFTR protein in airway epithelial cells leads to abnormally viscous mucus and impaired mucociliary transport, resulting in...

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Detalles Bibliográficos
Autores principales: Berical, Andrew, Lee, Rhianna E., Randell, Scott H., Hawkins, Finn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6376457/
https://www.ncbi.nlm.nih.gov/pubmed/30800069
http://dx.doi.org/10.3389/fphar.2019.00074

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6376457/
https://www.ncbi.nlm.nih.gov/pubmed/30800069
http://dx.doi.org/10.3389/fphar.2019.00074

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