Nuclear Entry of CRTC1 as Druggable Target of Acquired Pigmentary Disorder

Rationale: SOX10 (SRY-related HMG-box 10) and MITF-M (microphthalmia-associated transcription factor M) restrict the expression of melanogenic genes, such as TYR (tyrosinase), in melanocytes. DACE (diacetylcaffeic acid cyclohexyl ester) inhibits melanin production in α-MSH (α-melanocyte stimulating...

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Detalles Bibliográficos
Autores principales: Yun, Cheong-Yong, Hong, Seung Deok, Lee, Young Hee, Lee, Jiyeon, Jung, Da-Eun, Kim, Ga Hyun, Kim, Song-Hee, Jung, Jae-Kyung, Kim, Ki Ho, Lee, Heesoon, Hong, Jin Tae, Han, Sang-Bae, Kim, Youngsoo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6376463/
https://www.ncbi.nlm.nih.gov/pubmed/30809299
http://dx.doi.org/10.7150/thno.30276

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6376463/
https://www.ncbi.nlm.nih.gov/pubmed/30809299
http://dx.doi.org/10.7150/thno.30276

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