Epigenetic Co-Deregulation of EZH2/TET1 is a Senescence-Countering, Actionable Vulnerability in Triple-Negative Breast Cancer

Triple-negative breast cancer (TNBC) cells lack the expression of ER, PR and HER2. Thus, TNBC patients cannot benefit from hormone receptor-targeted therapy as non-TNBC patients, but can only receive chemotherapy as the systemic treatment and have a worse overall outcome. More effective therapeutic...

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Detalles Bibliográficos
Autores principales: Yu, Yong, Qi, Jingjing, Xiong, Jieyi, Jiang, Liping, Cui, Di, He, Junlin, Chen, Ping, Li, Lianjie, Wu, Chenjie, Ma, Tonghui, Shao, Su, Wang, Jianjun, Yu, Dansong, Zhou, Bing, Huang, Dongsheng, Schmitt, Clemens A., Tao, Ran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6376470/
https://www.ncbi.nlm.nih.gov/pubmed/30809307
http://dx.doi.org/10.7150/thno.29520

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6376470/
https://www.ncbi.nlm.nih.gov/pubmed/30809307
http://dx.doi.org/10.7150/thno.29520

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