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Pharmacological inhibition of autophagy by 3-MA attenuates hyperuricemic nephropathy

Autophagy has been identified as a cellular process of bulk degradation of cytoplasmic components and its persistent activation is critically involved in the renal damage induced by ureteral obstruction. However, the role and underlying mechanisms of autophagy in hyperuricemic nephropathy (HN) remai...

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Detalles Bibliográficos
Autores principales: Bao, Jinfang, Shi, Yingfeng, Tao, Min, Liu, Na, Zhuang, Shougang, Yuan, Weijie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6376616/
https://www.ncbi.nlm.nih.gov/pubmed/30293967
http://dx.doi.org/10.1042/CS20180563