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κ-Opioid receptor stimulation reduces palmitate-induced apoptosis via Akt/eNOS signaling pathway

BACKGROUND: This study was designed to test the hypothesis that κ-opioid receptor (κ-OR) stimulation reduces palmitate-induced HUVECs apoptosis and to investigate its mechanisms. METHODS: HUVECs were subjected to sodium palmitate, apoptosis and cell viability were determined, HUVECs were treated wit...

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Detalles Bibliográficos
Autores principales: Cui, Yan, Feng, Na, Gu, Xiaoming, Fu, Feng, Li, Jun, Guo, Haitao, Liu, Yali, Zhang, Shumiao, Li, Juan, Wang, Yuanbo, Jia, Min, Yang, Lu, Zhang, Fuyang, Wang, Yuemin, Fan, Rong, Pei, Jianming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6376663/
https://www.ncbi.nlm.nih.gov/pubmed/30764838
http://dx.doi.org/10.1186/s12944-019-0989-4