Cargando…
κ-Opioid receptor stimulation reduces palmitate-induced apoptosis via Akt/eNOS signaling pathway
BACKGROUND: This study was designed to test the hypothesis that κ-opioid receptor (κ-OR) stimulation reduces palmitate-induced HUVECs apoptosis and to investigate its mechanisms. METHODS: HUVECs were subjected to sodium palmitate, apoptosis and cell viability were determined, HUVECs were treated wit...
Autores principales: | Cui, Yan, Feng, Na, Gu, Xiaoming, Fu, Feng, Li, Jun, Guo, Haitao, Liu, Yali, Zhang, Shumiao, Li, Juan, Wang, Yuanbo, Jia, Min, Yang, Lu, Zhang, Fuyang, Wang, Yuemin, Fan, Rong, Pei, Jianming |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6376663/ https://www.ncbi.nlm.nih.gov/pubmed/30764838 http://dx.doi.org/10.1186/s12944-019-0989-4 |
Ejemplares similares
-
Icariside Ⅱ Attenuates Palmitic Acid-Induced Endothelial Dysfunction Through SRPK1-Akt-eNOS Signaling Pathway
por: Gu, Yang-Yang, et al.
Publicado: (2022) -
Ang (1–7) Protects Islet Endothelial Cells from Palmitate-Induced Apoptosis by AKT, eNOS, p38 MAPK, and JNK Pathways
por: Yuan, Li, et al.
Publicado: (2014) -
Berberine Protects against Palmitate-Induced Endothelial Dysfunction: Involvements of Upregulation of AMPK and eNOS and Downregulation of NOX4
por: Zhang, Ming, et al.
Publicado: (2013) -
κ-opioid receptor stimulation alleviates rat vascular smooth muscle cell calcification via PFKFB3-lactate signaling
por: Niu, Jin, et al.
Publicado: (2021) -
κ-Opioid Receptors Improve Vascular Endothelial Dysfunction in Salt-Sensitive Hypertension via PI3K/Akt/eNOS Signaling Pathway
por: Wu, Qi, et al.
Publicado: (2023)