Efficient two-step multivariate random effects meta-analysis of individual participant data for longitudinal clinical trials using mixed effects models

BACKGROUND: Mixed effects models have been widely applied in clinical trials that involve longitudinal repeated measurements, which possibly contain missing outcome data. In meta-analysis of individual participant data (IPD) based on these longitudinal studies, joint synthesis of the regression coef...

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Detalles Bibliográficos
Autores principales: Noma, Hisashi, Maruo, Kazushi, Gosho, Masahiko, Levine, Stephen Z., Goldberg, Yair, Leucht, Stefan, Furukawa, Toshi A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6376708/
https://www.ncbi.nlm.nih.gov/pubmed/30764757
http://dx.doi.org/10.1186/s12874-019-0676-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6376708/
https://www.ncbi.nlm.nih.gov/pubmed/30764757
http://dx.doi.org/10.1186/s12874-019-0676-1

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