Cargando…

Mst1-Hippo pathway triggers breast cancer apoptosis via inducing mitochondrial fragmentation in a manner dependent on JNK–Drp1 axis

BACKGROUND AND OBJECTIVE: Mst1-Hippo pathway and mitochondrial fragmentation participate in the progression of several types of cancers. However, their roles in breast cancer requires investigation. The aim of our study is to determine whether Mst1 overexpression regulates the viability of breast ca...

Descripción completa

Detalles Bibliográficos
Autores principales: Ouyang, Hui, Zhou, Enxiang, Wang, Huan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6376886/
https://www.ncbi.nlm.nih.gov/pubmed/30809096
http://dx.doi.org/10.2147/OTT.S193787