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Elevated Human Dipeptidyl Peptidase 4 Expression Reduces the Susceptibility of hDPP4 Transgenic Mice to Middle East Respiratory Syndrome Coronavirus Infection and Disease
BACKGROUND: The ongoing Middle East respiratory syndrome coronavirus (MERS-CoV) infections pose threats to public health worldwide, making an understanding of MERS pathogenesis and development of effective medical countermeasures (MCMs) urgent. METHODS: We used homozygous (+/+) and heterozygous (+/−...
Autores principales: | Algaissi, Abdullah, Agrawal, Anurodh S, Han, Song, Peng, Bi-Hung, Luo, Chuming, Li, Fang, Chan, Teh-Sheng, Couch, Robert B, Tseng, Chien-Te K |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6376904/ https://www.ncbi.nlm.nih.gov/pubmed/30256968 http://dx.doi.org/10.1093/infdis/jiy574 |
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